Nestled in the heart of Mesa Grande, this exceptional 168± acre ranch in Santa Ysabel offers a rare opportunity to own a truly private, off-grid retreat in one of Southern California’s most desirable and storied backcountry regions. Surrounded by generational ranches and characterized by rolling pastures, oak woodlands, and native chaparral, the land is fully fenced and features a blend of usable terrain and natural beauty—ideal for grazing, agriculture, or development of a custom ranch or retreat. Enhancing its allure is the ranch’s coveted exclusivity, secured by gated access and well-maintained ranch roads, ensuring both privacy and accessibility. A thoughtfully converted barn anchors the property, offering approximately 1,500+/- square feet split between a versatile workshop and a comfortable apartment. Completely off-grid with independent utilities, this setup is perfect for sustainable living, weekend getaways, or as a functional base while developing the land further. With direct highway frontage along scenic Mesa Grande Road, the ranch is easily accessible year-round, and a meandering driveway and network of trails provide seamless navigation through the breathtaking landscape. Multiple potential custom home sites offer panoramic views and a canvas for future vision. The surrounding region only adds to the lifestyle potential. Outdoor enthusiasts will enjoy proximity to Lake Henshaw, the Santa Ysabel Open Space Preserve, and nearby trails ideal for hiking, horseback riding, and exploration. The nearby historic town of Julian provides a taste of small-town charm, with boutique wineries, cideries, farm-to-table restaurants, and renowned stops like the Julian Pie Company. Whether seeking adventure or tranquility, the area offers a balance of recreation and rural luxury. With favorable A72 agricultural zoning and an “O” Animal Designator, and a solid producing private water well, the property can support a wide array of agricultural endeavors—from equestrian estates and livestock operations to organic farming and viticulture. Ranches of this caliber are seldom offered and represent a coveted opportunity for the discerning steward to cherish a slice of the beautiful San Diego backcountry.