Set behind private gates at the end of a long, tree-lined driveway with a circular motor court, 16733 Calle Hermosa is a one-of-a-kind estate offering resort-style living, timeless architecture, and unrivaled privacy in the Artesian Estates. Surrounded by scenic lemon groves, citrus trees, and mature landscaping, this 3.57-acre retreat blends natural beauty with thoughtfully curated design and modern comforts. Built in 2008 and maintained with meticulous care, the main residence (5,545 SF) exudes quality and warmth. A courtyard entry welcomes you with a fireplace and fountain, while the interiors feature soaring ceilings, oak wood floors, and abundant natural light. The grand great room—with two-story windows, exposed beams, custom lighting, a stunning stone fireplace, and six sets of French doors—anchors the home and flows effortlessly to a covered loggia and the resort-style pool deck beyond. The chef’s kitchen is a dream, complete with a 70" Frigidaire Professional refrigerator, Dacor 6-burner range, double-door ovens, two sinks, dual Fisher & Paykel dishwasher drawers, a walk-in pantry, and breakfast nook—perfect for family meals or entertaining. Just off the kitchen, the inviting family room features a second stone fireplace with a custom designer screen. The main level also includes the spacious primary suite with serene views and a spa-like bath, plus a secondary en-suite bedroom currently used as a home office. Upstairs, two additional en-suite bedrooms offer sizable closets and beautifully appointed baths, creating private havens for family or guests. Complementing the main home is a 918 SF detached guest house with full kitchen, living room, bedroom, and bath—ideal for multigenerational living or visitors. A 529 SF pool house offers a covered loggia for entertaining and includes a secondary garage/storage area beneath - perfect for a home gym, studio, or hobbyist’s space. The outdoor living experience is exceptional. Enjoy a sparkling pool and spa, Cantera stone patios, a covered dining area, outdoor speakers, and wide lawns for recreation. The fenced lot offers tremendous versatility, with room to add a vineyard, tennis or pickleball court, equestrian facilities, or even a collector’s garage. All four water heaters have been recently replaced, and the property is equipped with a fire sprinkler system, septic, Cox high-speed cable, and more. Zoned for both Solana Beach/San Dieguito and Poway Unified School Districts, the location offers flexibility for families and easy access to top public and private schools, freeways, shopping, and coastal destinations. This extraordinary estate delivers the ultimate in Southern California living—a turnkey sanctuary that feels brand new, offering elegance, privacy, and endless opportunity on one of Artesian’s most usable parcels.